Direct TV’s Technology Complements Its Programming

While it’s well known that Direct TV provides a wide variety of high quality programming on hundreds of television and satellite radio channels, not many people know about the impressive space age satellite technology that goes into delivering that programming to over fifteen and a half million subscribers.

While there are some types of technology that are available on special order, Direct TV also provides some pretty impressive technology to all of its subscribers regardless of which programming package they sign up for. The most basic technology is digital television. Television programming in digital format provides a vividly crystal clear picture in all but the worst weather conditions. That’s because digital television is easily cleansed of any interference that it picks up during transmission by Direct TV’s sophisticated satellite receiver equipment.

Direct TV also provides great user friendly software to all of its subscribers. User friendly software like the on screen program guide and Parental Locks make it much easier to handle the hundreds of channels that you could have available to you if you sign up for one of the larger programming packages. The on screen program guide is probably the piece of software that you’ll use the most. It displays a listing of all of the television shows and movies that you can choose among right on your TV screen. Along with each program, the on screen program guide will also provide you with information about the program- like who stars in it and what the plot consists of- in order to help you decide whether or not it’s something you might want to watch. While the on screen program guide is on the screen, the picture from the channel that the system is tuned to will continue to be displayed in a small window in the corner of the screen and the audio will continue to play over the speakers. That way you won’t have to miss anything while you’re looking around.

Direct TV’s Parental Controls help you to manage all of the channels, by providing you with tools to prevent your children from watching inappropriate programming. You can enact blanket rules, like blocking access to all movies with certain MPAA ratings, or you can block out specific programs and channels. Parental Controls are extremely flexible tools that can provide you with all the peace of mind you need to leave your kids alone with the TV.

One of the optional technologies you can get from Direct TV is a Digital Video Recorder. Digital Video Recorders are built into some satellite receivers and provide a great way to record the TV shows and movies that you want to watch, but wouldn’t otherwise be able to see because of other obligations like work, family, and community. This practice of recording programming so that it can be watched later is called “time shifting” and a Digital Video Recorder is extremely useful for “time shifting” because it’s easy to program, can store a huge amount of video on its hard disk, and even record video from two separate channels at the same time! As an added bonus, all of the video that it records is stored and played back with the same high quality picture and sound of Direct TV’s original broadcast.

Another optional technology supplied by Direct TV is HDTV. HDTV is a next generation television format that features a high resolution picture and wide screen along with a sophisticated sound format. All of these differences mean that you need a special TV set, a special receiver, and special programming to watch HDTV. Direct TV can provide everything that you need to enjoy this technology right now, except for the HDTV set.

Direct TV provides a lot of great technology that will enhance your television experience.

Preformulation and Formulation Development

Optimizing Conformational Stability and Biological ActivityMaintenance of the native three dimensional conformation is critical for the long term stability and biological activity of biotherapeutics. Biophysical characterization techniques such as circular dichroism, differential scanning calorimetry, FTIR, dynamic light scattering, and fluorescence spectroscopy provide a mechanism to assess the conformational and thermodynamic stability of proteins under a range of formulation conditions. These tools allow development scientists to differentiate various various buffer, pH, ionic strength, and excipient conditions, and identify the conditions that confer the optimum environment for the therapeutic protein.

Utilizing Advanced Statistical Design for Preformulation Development Preformulation development includes statistical design of experiments, allowing simultaneous evaluation of multiple factors and evaluation of interactions between factors. It is crucial to use advanced biophysical characterization techniques to evaluate the conformational stability of large molecules in addition to traditional methods for evaluation of chemical stability.

A large molecule preformulation development program typically includes the following activities:
Evaluate the effect of pH, buffer type, and ionic strength on solubility.
Evaluate the effect of various excipients on improving solubility if necessary.
Evaluate effects of pH, buffer type, and excipients on conformational stability.
Evaluate the effect of pH, buffers, excipients and ionic strength on physical and chemical stability.
Utilize a statistical design approach to identify the optimal conditions for structural, physical and chemical stability.
Perform forced degradation to elucidate product degradation pathways and to demonstrate the stability-indicating capacity of the analytical methods.
Forced degradation studies typically include restricted oxidation, deamidation, aggregation (via agitation), and / or acid / base hydrolysis.
Evaluation of heat stress, photo stress, and freeze thaw are also performed.

Looking for information on Analytical Development and other related resources?

Formulation Development for Numerous Dosage FormsFormulation development includes dosage forms for parenteral, oral topical and inhalation administration, including liquids, gels, suspensions, emulsions and lyophilized powders. Formulation scientists are highly skilled in the development of the dosage forms most relevant to biotherapeutics, with particular expertise in lyophilization and development of stable liquid formulations for proteins. High concentration antibody formulation development for subcutaneous administration requires particular emphasis on viscosity and tonicity. Lyophilization cycle development is performed in the context of the unique thermodynamic properties of the API to deliver an efficient, scalable, transferable process resulting in optimum product stability and reconfiguration characteristics. Formulation development capabilities also include:

Effect of excipients on solubility, tonicity, and viscosity Evaluation of antioxidant and conservative compatibility Container-closure compatibility Long term and accelerated stability studies.

Advantages of Formulation Development Approach. This outlined approach to preformulation and formulation development result in significant savings to the client by eliminating the variables associated with suboptimal formulations. Preclinical development efforts in PK, PD, ADME and toxicology occur with confidence that additional uncontrollable variables from unstable formulations are not introduced into the study. This benefit extends far into clinical trials as well, where assessment of toxicity, dosage levels and efficiency are substantially influenced by an optimal formulation that preserves the three dimensional conformation of the therapeutic protein. By eliminating uncontrolled stability variables, the focus is placed solely on the therapeutic performance and clinical outcome.

Birthday Gag Gifts

A gag gift for a birthday is way cooler than an ordinary, useable gift. Give the following gag gifts to your loved ones, and see how the person will love you more.

For the always late officemate, give him a backwards clock. Written in reverse, this clock will definitely drive your officemate nuts in no time.

For your conceited teenage sister, give her the laughing mirror. This is the mirror that will laugh every time someone grabs hold of it and looks into it. Your sister would definitely love you more when she gets laughed at by the laughing mirror!

Give fake cat poop to your obsessive-compulsive friend. Scatter it all over her bedroom floor, or, better yet, on her mattress to make her birthday complete.

For your love-sick aunt, give her the art of kissing book. So when she reads it, she gets to crave someone to do the kissing with. For additional fun, include the barf-scent breath freshener so she can enjoy her kissing moments even more!

Your long-haired rocker friend describes the bald head wig. This way, he can have the feeling of having a shaved head for a little while. Or maybe he can even pretend to be a hard-core punk!

The exploding lighter coupled with the exploding cigarette pack is perfect for your buddies who incessantly smoke every time you are together. Nothing will make their day better and your day more hilarious than playing this great prank on them!

If you want your loved ones to love you even more, make sure you give them meaningful gifts that will stick in their memories for the longest time. For that to happen, gag gifts are your best choice.

What Is Digital Marketing and How to Use It

You will have to devote lots of time marketing yourself and earning referrals. Content marketing thus will be more prone towards user-generated, instead of professional, content within the next calendar year. The secret to content marketing is that the content has to be interesting to your audience and will supply value to them.

There are a number of reasons to put money into influencer advertising. It is a way to get past the need to use ads to reach your audience. Though email promotion is highly effective, not all startups can harness the real power of email marketing.

Digital marketing isn’t rocket science. It has no boundaries. Since you may see, digital promotion is a big and complicated topic. Digital Marketing is a huge subject and you cannot turn into a hero in 30 hours! It is a type of marketing technique where the marketing activity is carried out with the help of channels and platforms available on the internet. It uses the internet as a main promotional medium, in addition to traditional TV and radio.

It is one of the fastest growing industries so there is much room for growth and development. It is one of the top 5 growing sectors since the year 2009. In simple terms, it is the promotion of products, services or brands via digital marketing channels. It is much more advanced than the traditional style of marketing because, One has to be very careful in selecting the right strategy to generate reach.

Getting your very own digital advertising and marketing blog is able to help you set yourself apart from others in the business and stand out when you should speak to an influencer or potential employer. The ideal marketing influencers are individuals who speak and reveal themselves in front of individuals.

Your email marketing strategy will vary a lot based on the essence of your small business. Needless to say, there are a number of different reasons your data-driven advertising and marketing strategy could fail in addition to a deficiency of comprehensive tools. It’s simple to separate your digital advertising strategy into various channels like pay per click ads, social networking, search engine optimisation and so forth. A digital marketing and advertising strategy does not necessary demand a detailed analysis, it merely takes a set of objectives and goals which you are seeking to realize. You should develop a content marketing strategy based not just on the info you need to give your clients, but also based on your understanding of what information people are trying to find.

Your digital marketing and advertising strategy might incorporate elements of all 3 channels, all working together to assist you achieve your objective. An intelligent and powerful digital marketing and advertising strategy has many faces. Then you’ll have a fully integrated digital marketing and advertising strategy.

Developing a digital marketing and advertising strategy does not need to be hard work. Based on the scale of your organization, your digital marketing strategy might involve a number of objectives, but coming back to this easy manner of thinking about strategy will be able to help you stay focused on meeting those objectives. It needs to deliver the right content based on their buying stage. A clearly defined digital marketing and advertising strategy encourages existing customers together with new customers to engage and stay loyal.

You need to construct a marketing system which focuses on a group or groups of individuals. The key issue is to develop your promotion system with the most suitable expectations. Fortunately, marketing software has come a very long way in the past few decades, and there are a lot of tools which may help. Ask yourself these questions before you pick any new marketing and advertising tool. You are going to learn how to use the digital instruments and techniques effectively for a prosperous campaign. In other words, it’s because digital instruments and skills have an established capacity to create revenue, and companies wish to harness that power and keep competitive.

Using digital radiography has rapidly increased in recent decades. You could also take advantage of sophisticated email marketing software to run targeted campaigns with an objective of convincing your audience to have a particular action such as signing up for a class, buying your goods, attending an event, or in any case may be. It explains using email marketing, online affiliate marketing, Facebook marketing, and the way to use social networking tools like Twitter, podcasting and blogging.